AIDS breakthrough shows what science can do

We now live in an age when science (and the rational habits  of mind it depends upon) is under attack.  Heirs to the rational tradition have always had to live with religious fundamentalists who deny inconvenient truths like evolution. But nowadays attacks come thick and fast from those who wish to deny  climate change, the dangers of  smoking, the efficacy of vaccines and much besides.   From people who nevertheless cheerfully accept other scientific findings which suit them.   So, just to redress the balance we thought we’d showcase this breathtaking new advance in AIDS research which, for the first time, holds out the hope of a permanent cure.

It comes from Kat Lay of the Guardian,[1] reporting the  work of the Peter Doherty Institute in Australia.[2] The background will be familiar: the great evolutionary survival trick of the HIV was to bury itself deep in certain white blood cells of the immune system, where it was immune to our attack. In the words of Kat:

In a paper published in Nature Communications, the researchers have shown for the first time that mRNA can be delivered into the cells where HIV is hiding, by encasing it in a tiny, specially formulated fat bubble. The mRNA then instructs the cells to reveal the virus. First AIDS was a death sentence: then it could be slowed with drugs. Now at last comes hope of a real cure for its 40 million or so sufferers

Science itself is a process, not a monolithic entity. It evolves, refines, and corrects itself over time. But when people selectively accept only the parts that align with their worldview, they undermine the very foundation of rational inquiry   This kind of cherry-picking often stems from cognitive biases, ideological commitments, or economic incentives. Climate change denial, for example, is frequently tied to political or financial interests, while opposition to vaccines or smoking regulations can be fuelled by misinformation or personal convenience.  But the deniers should remember one thing: if they do decide to overthrow the rationalists, will they put anything better in our place?

Truth is compared in Scripture to a streaming fountain; if her waters flow not in a perpetual progression, they sicken into a muddy pool of conformity and tradition.”

 Milton: Areopagitica

[1]https://www.theguardian.com/global-development/2025/jun/05/breakthrough-in-search-for-hiv-cure-leaves-researchers-overwhelmed?CMP=Share_AndroidApp_Other

[2]https://www.doherty.edu.au/

#HIV #AIDS #disease #mRNA #medicine #science #climate change #smoking

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