


Once again, the source for our blog today comes from the excellent Nature Briefing, who are always in the forefront of scientific research in every field. Today we are showcasing their piece AI is taking on antibiotic resistance because we think they’re picking up on some real game-changing developments, and we really want you to know about them.
Let’s start with their usual helpful summary, as it’s a good general overview. But this time we earnestly beg you to click on the link they have provided: read below to find out why.
Antibiotics are an effective, but somewhat indiscriminate solution to some gut infections. Helpful species of gut bacteria get caught in the crossfire, which increases the likelihood that drug-resistant bacterial strains will evolve. Researchers are now designing drugs to selectively target disease-causing species with the help of artificial intelligence. Some teams are using AI to screen drug molecules for the most promising candidates quickly and cheaply. Others have developed tools that predict how drug molecules bind to protein targets to reveal a drug’s mechanism of action, reducing the need for wet-lab experiments.
Because if you do, you will step into a world of research where Information Science and Biological Science are meeting: which of course is more and more these days isn’t it? You will learn about:
Jonathan Stokes of McMaster University in Canada who have pioneered the use of AI to test their newest molecule called enterololin and thereby strip out all kinds of old-skool testing processes.
Regina Barzilay of MIT who with her team have done much of the AI work to set this up for Jonathan She is a remarkable woman who has been hunting down the link between antibiotics and AI since 2018-how’s that for far sightedness, folks?
You’ll be able to name check tools like Diffdock , RdKit and Chemprop which these people use to do all this-how’s that going to sound in the pub?
And a woman called Molly Bartlett who’s something called a Chemical Informatician at London’s Imperial College. As we still have a tenuous connection to that august institution we sometimes write in to their alumnus mag and tell them what a good job they’re doing, knowing we speak for all of you, gentle readers.
And much more besides, Especially if you do the decent thing and sign up to go behind the paywall.
Funny, isn’t it? If our first name were Donald (it isn’t) we might note how much this progress a) seems to come from despised places like Canadia and Englandland b) how somehow these evil foreigners still find ways to work with Unitedstatespersons c) maybe if you want to find cures for important things you may have to look at other methods in addition to earnest prayer d) if I were getting bigly older, perhaps approaching my eightieth birthday for example, I might like to have a few antibiotics around. Just a thought.
# Antibiotic research #Artificial Intelligence ~medicine #health #bacteria


























