


Ever attentive to our readers’ clamour for more good news on antibiotic resistance we bear yet another story on the synthesis of Artificial Intelligence with the frontiers of cellular biology to produce yet another remarkable advance. Yet we think, gentle readers, that this story may have far deeper significance for the evolution of life on this planet and who knows, several of the neighbouring ones in our Solar System, and today we will tell you why.
First the story, showcasing the work of the assiduous James Gallagher of the BBC.[1] Researchers at Stanford University[2] have used the AI systems Evo 1 and Evo 2 to design a new generation of entirely synthetic bacteriophages which have already proved effective against certain strains of E.coli. We will let our links tell the story of the ingenious Brian Hie and Samuel King and what their teams have accomplished: but regular readers will realise what a valuable new therapeutic technique this could be. Good journalist that he is, Gallager covers certain warnings too: but that is the BBC for you: balanced, nuanced and still true to its Reithian principles 100 years on.
But if you will forgive us, we think this is our opportunity to record why we think all this AI-meets-biology trope we have been covering for some years is truly significant. And it is this. For millions of years, organisms under attack-by parasites, predators, whatever- have relied on the slow, wasteful grind of Darwinian natural selection to stumble toward defence. Now, for the first time, a host species has stepped outside that blind process. With AI‑designed bacteriophages, the human brain—admittedly an organ shaped by old school evolution—is beginning to direct its own evolutionary responses by compressing what once took thousands of generations into deliberate, rapid invention. Not synthetic life, exactly, but something stranger: synthetic evolution. And, if human attempts to colonise the moon and nearby planetary systems are successful, these may be the new sorts of life forms that come to inhabit those worlds. Not sad old Darwinian selected eucaryotes like ourselves and our pet cats. Just a thought.
With thanks to Mr G Herbert and our in-house team of researchers who implored us to break our weekend embargo to bring you this story
[1]https://www.bbc.co.uk/news/articles/c5y3j3ngevmo
[2] AI designs a novel E. coli killer | Stanford Report
#AI #bacteriophages #genomes #health #medicine #antibiotic resistance #evolution #biology #future

























