Is this why exercise helps you to live longer?

We won’t spend too much time setting up the showcase for today’s blog. Because Nature Briefing does the whole thing much better, via this piece Bones might hold an anti-ageing secret, so we’ll let you read it and make a couple of our stock in trade observations at the end

The mechanical strain placed on the skeleton during physical activity might prompt bones to release proteins that slow ageing, a study in mice suggests. Researchers found that gently squeezing the legs of mice to simulate the movement of exercise triggered force-sensing cells called osteocytes to secrete molecules that rejuvenate immune cells and reprogram cells in other organs to a younger state. Mice that went through this faux exercise regime lived around three months longer on average than did mice that didn’t.

Science | 5 min read
Reference: Cell Metabolism paper

Just when we think we’ve found all the tricks, along comes another one: apparently our bones may have been quietly manufacturing anti-ageing signals all along. Which only goes to show. We know that regular physical activity reduces chronic inflammation, helps maintain muscle and bone, improves the body’s response to insulin and keeps the heart and blood vessels in better working order. [2] Which leads us to another thought: why are all those bans on cars, speed restrictions and pedestrian areas really such bad ideas? Next time someone starts banging on about them in the pub, you’ll know why they’re wrong.

[2] Benefits of exercise – NHS

#health #transport #cars #skeleton #exercise #fitness #bone #pollution

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