AI-designed antibiotics: more good news to report

This is getting to be a habit. About a year ago we showcased a story about the redoubtable Professor de la Fuente and his team at the University of Pennsylvania who were starting to use AI for the development of new antibiotics. (LSS 6 6 2024). Since when our optimism has been justified seven fold over and seven, to coin a phrase. For today we are genuinely excited to bring you this story from James Gallagher of the BBC which takes things up to the next stage. [1]

Because another redoubtable Professor, one James Collins and his team at MIT have now used AI not only to identify potential new antibiotics, but also to synthesise them and prepare them for testing. What’s more, they’re going to try them out on MRSA and gonorrhoea, two recalcitrant old lags which have long frustrated researchers, as our long term readers will recall

The story ticks quite a few more LSS boxes with institutions like Imperial College and the Fleming Fund getting quotes. At last, things seem to be coming together. When we started our antibiotics obsession, ten long years ago, we foresaw the current civilisation collapsing under unstoppable plagues, just like the Roman one before us did. But if it does, it may not be for lack of new antibiotics: we feel we can say that much now. Plenty of lethal threats still confront us, from Global warming to the threat of nuclear war. And the recent collapse of the talks designed to limit plastic pollution is a shameful reminder of the cognitive limits of our species..[2] But: just occasionally, something can be done about something. Maybe that’s hope , for all we know.

[1]https://www.bbc.co.uk/news/articles/cgr94xxye2lo

[2]https://www.bbc.co.uk/news/articles/cvgpddpldleo

#artificial intelligence #antibiotics #antibiotic resistance #MRSA #MIT

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