More good news on dementias

Dementia is our own internal pollution. Clear that pollution away, and the brain may start to function well again. If the systems which clear it slow down with age, then of course you won’t think so well. That is the startling new research reported today in the Mail by the admirable Syeeda Saad. [1] According to Syeeda and the rather clever scientists whom she channels, the brain is well equipped with these clearance systems when we are born. [2] They go by such recondite names as microglia, glymphatic and lymphatic systems. They clean up all the horrible waste we produce as we think-bits of cells, proteins, toxins, what have you. If they don’t, you accumulate all this detritus and your brain slows down, exactly like a sewage system blocked with fatbergs (yuck!-ed) [3]

Essentially the ingenious researchers target lymphatic networks outside of the brain in order to boost the clean-up systems within it. And get this-they have found new pathways called T Cell gateways which let them overcome the blood brain barrier, a wall that has bedevilled researchers for decades. [3]

All in all rather hopeful. Though as everyone admits these discoveries are at the early, tentative stage. Meanwhile there are lots of proven methods we can apply in order to reduce the risk of developing dementias. Including unpleasant ones like eating less junk food, drinking less booze and getting more exercise. There’s a thought. And here’s another to close. The team of scientists who did all this useful, public spirited, and one day profitable research are based at Washington University in the United States of America, What will become of them and their University in the financial and intellectual climate currently prevailing in that fallen country?

[1]https://www.dailymail.co.uk/femail/article-14560527/neuroscientist-remove-brain-waste-prevent-dementia-age.html

[2]https://www.vice.com/en/article/clearing-brain-waste-could-prevent-dementia-in-the-future/

[3]https://www.nature.com/articles/nature14432

#alzheimers #dementia #brain #t cells #lymphatic #medicine #health

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