In praise of the Limoncello Spritz

Today we are going to praise a great Italian export. Not stylish cars, nor sharp suits. Nor even pasta or Renaissance Art. No, we are going to go with the Limoncello Spritz, a delightful cool, sparkling drink that will gladden many a warm summer evening.

And it’s so easy to make! Just a bit of ice, a little prosecco or other white sparkler, soda water (all really cold by the way) and of course the delightful, but fearsomely powerful liqueur which the Italians call Limoncello (yup, they really do make it from lemons), There are many good sites on the interweb for recipes and background info: we have chosen this one from sip and feast- we liked their bright, breezy style which perfectly captures the feel of this cocktail [1]

We could cite many reasons for this evening’s recommendation. The advice of seasoned travellers (before this year our experience on the Italian peninsula was effectively zero).The simplicity and authenticity of the drink (apparently they all love it over there) But we freely confess that our recommendation is based on our time in a certain hotel in Rome, close to the famous Baths of Diocletian and Maxentius. For there we could sit at an elegant marble bar, shelves and accessories all blended to match, while equally elegant and well-dressed waiters served up the hooch with that friendly charm for which Italians are famous. While outside the picture windows, the busy life of Rome slipped by, all Armani suits, motor scooters and noisy families. Rushes from Fellini, we wondered?: or passages from Calvino?

Italy has contributed more than almost any other country to human advancement and progress: dare we add the Limoncello Spritz to the illustrious roll-call of their achievements?

[1]https://www.sipandfeast.com/limoncello-spritz/

limoncello spritz #cocktail #italy #rome

Antibiotics: the last line of defence has just failed

Amid all the talk of riots, of Mr Trump and the Olympics, a deadly killer has evolved. Quietly, stealthily it has begun to take its toll. And like an army that suddenly realises it has run out of ammunition, Doctors may have nothing to check its advance.

Because a certain strain of Klebsiella bacterium, called hvKvs123 has now become resistant to carbapenems, the last type of antibiotic known to be effective against it. We can’t do better than to urge you to click on this story by the ingenious John Ely of the Mail whose explanations and graphics are of the first order.[1] But we can fillet out a few facts from it which convey the true gravity of the situation we now confront. Firstly, the new strain has been found in over 17 countries,many of them poor and overcrowded, which are ideal conditions in which it will spread. Figures from the UK suggest that its resistant capacity is rising very fast indeed, from 13.5% in 2018 to 17.4% now. While cases of resistance have leapt from 9 802 to a 11823 (to put that in perspective road deaths were only 1, 711) Finally, Klebsiella is responsible for up to 30% of cases of pneumonia. It could be an interesting winter, especially for those of us who are too poor or to hungry to heat our homes.

Is this the start of the next pandemic? Old LSS hands will know that we are always pushing the antibiotics trope here. But we are the first to admit that it’s not the only possible cause. However, two things worry us today. The near total breakdown of carbapenems and the fact there is now no substitute means that we will be fighting this pandemic always from one step behind. Secondly, that Klebsiella is such a common organism, thriving in places like the respiratory tract from which it can disperse easily. These two features alone put it will up on the starting grid for next-pandemic candidates. And one thing you can be sure of, gentle reader. That pandemic will come. Soon.

[1]https://www.dailymail.co.uk/health/article-13714121/superbug-16-countries-klebsiella-pneumoniae-antibiotic-resistance.html

[2] https://en.wikipedia.org/wiki/Klebsiella

#pandemic #antibiotic resistance #olympics #donald trump

The Rubber Economy is back-and it’s gold

During the Second World War, a wag once remarked that the British Economy was like rubber, stretching itself in more and more directions to meet the efforts of arms production, food and all the other urgent requirements of the time. Economic historians record Herculean efforts at production. And equally ingenious efforts to scrimp, save and recycle to ensure that nothing useful was wasted. It was a long time ago, but could we still learn something from those days?

Britain’s Royal Mint thinks so. There job is to make all our coins, which they have been doing for hundreds of years. Some are made of gold ; and as they have astutely noted, the price of that metal has been soaring in recent years. Where to get more? Well something else has been soaring: the amount of high tech rubbish we all throw away so heedlessly. (not YOU, gentle reader: everyone else) Mobile phones, computers, entertainment systems of all kinds. Billions of items, thousands of tonnes. Well there may be a lot of gold in it, at concentrations higher than the ores processed by all those rugged manly chaps out in the mines and factories. And as Rebecca Morelle and Alison Francis report for the BBC the Royal Mint is now starting to mine it for gold, big time and turning the shiny stuff into lovely coins. How’s that for recycling. How’s that for a thoughtful use of resources in difficult times.

And the moral in all this? We in the LSS community (and the educated community more widely) are still members of the human family. It’s just that certain members of our family are highly unhappy, emotionally disturbed and not very nice. And this unhappiness comes out in things like drinking, violent emotional outbursts, riots, wars and things. But a family is a family. And the quieter sensible members get on because they have to. Inventing new technologies. Discovering new facts. Clearing up the mess. And we will continue to do so, until our day comes.

Question: How come Newsround had this in March and Big news didn’t get it until August? We don’t know either

[1]https://www.bbc.co.uk/news/articles/c6p2k11e41po

[2]https://www.bbc.co.uk/newsround/58971402

#gold #royal mint #recycling #waste #e waste

British Riots: We can’t do better than this article by Richard Fern

Foreign readers must be reeling in disbelief to see the home of Democracy (or at least representative government) and the bastion of law and order dissolving into ugly, uncontrollable race riots. Why? The whole business of tribalism, status anxiety, hierarchy and downright anger are themes we’ve tried to cover before on these humble pages (most recently LSS 12 7 24) But: we admit that somehow we have never quite got to then heart of the subject. Never quite captured its essence. Certainly not as well as Richard Fern of Swansea University, whose article for the Conversation is at once succinct and insightful. [1]

Richard points out how online trolls and agitators are adept at tapping into the deep pools of anger and resentment felt by many. As we have observed before in these pages, these feelings are rooted in a sense of helplessness, loss, bewilderment, powerlessness and a lack of any credible model of a better future. Attempts to counter such posts with rational facts are thereby useless. In this species, emotion will always blot out reason. At this moment, media attention is centred on irate white males. But by our logic, many ethnic and religious groups will also experience this disastrous syndrome.

And disastrous it will be. A reversion to a world of jealously polices ethnic rivalries will be neither stable nor happy. The histories of Northern Ireland, South Africa and Israel should be testament sufficient of that. Economic outcomes must be suboptimal, as each nation looks for autarky, breaking Adam Smith‘s prime rule of specialisation and free trade. Unless ways are found to prize openness and liberty over exclusivity, the future looks dark indeed.

#adam smith #autarky #race riot #anxiety #tribalism #southport

Discoveries at the root of life

Looking at the vast range of living creatures today makes us gasp at their diversity. From giant whales to tiny insects, and every imaginable variation in between. We know, from studies like genetics, embryology and fossils that all came from a single form. And that form had sufficient potential, enough plasticity in its DNA to slowly morph into every animal that has ever lived. What that earliest animal looked like, we can only conjecture, at the current state of knowledge. But there must have been quite an early diversification into creatures that at least represented the first members of the great phylae of animals. The first arthropod, the first vertebrate, the first mollusc ,nematode, and so on.

Two recent discoveries give us an exciting picture of what two of those may have been like: the first arthropod (ancestor of insects, spiders, shrimps, scorpions etc) And the first mollusc (ancestor to the amazing world of slugs, snails, clams and cephalopods). Researchers at Durham University have used advanced microscopical techniques to look at a tiny fossil [1] named Youti yuanshi which lived in what is now Yunnan about 520 million years ago. Details of its internal organs suggest it is close to the ancestors of all those jointy, segmented arthropods, probably the most successful and diverse group of animals on the planet. And not to be outdone, the molluscs have come up with their own Ur-ancestor, called Shishania aculeata, a kind of spiny slug which lived at around the same time. [2]

We will leave you to explore the details in the links which we have provided. We hope you will jump off from these to find out more. We will marvel at the skills and techniques of scientists who wring so much fresh learning from intricate new techniques. And above all at the window provided to the lives simple creatures in a warm sea half a billion years ago, who stood at the start of so much life.

[1]https://phys.org/news/2024-07-million-year-worm-fossil-mystery.html

[2]https://www.msn.com/en-gb/news/world/half-a-billion-year-old-spiny-slug-reveals-the-origins-of-molluscs/ar-BB1r2wNG?ocid=msedgntp&pc=HCTS&cvid=d0f78bd5cd7

#genetics #embryology #evolution #arthropod #mollusc #yunnan

A Round-up of Hope: Cancer,antibiotics, green energy and life on the red planet

A few science and health stories which prove there are still few intelligent people out there working for the common good

Mouth Bacteria may protect against cancer To beat cancer we need to think laterally at times, and take bits of luck when they come from unexpected discoveries. According to Xantha Leatham of the Mail, Scientists at London’s prestigious St Thomas Hospital may have done just that. It looks like the organism Fusobacterium may protect against certain types of neck cancer. We love these serendipitous discoveries by lab scientists-real shades of Alexander Fleming!

https://www.dailymail.co.uk/health/article-13676291/Common-mouth-bacteria-melts-cancer-scientists-explain-patients-better-survival-odds.html

Antibiotics for sepsis We scraped this straight from Nature Briefings, that most worthy source of scientific information Definitely a sign of progress, we think:

A method to quickly identify the bacteria involved in life-threatening sepsis — and which antibiotics will kill them— could save patient lives. Key to saving precious time are magnetic nanoparticles with bacteria-capturing molecules. They fish out the usually tiny number of microbes from a blood sample, so testers don’t need to wait for the bacteria to grow and multiply. “I think that this technology can be in one box within three years, and… within four years, it can be in the clinic,” says bioengineer and study co-author Sunghoon Kwon.Nature Podcast | 35 min listen
Subscribe to the Nature Podcast on Apple PodcastsSpotify or YouTube Music, or use the RSS feed.

EU powers ahead on renewables Like other big power blocks such as India and China, the EU is rapidly achieving crossover on renewable energy generation, as this article by Ajit Naranjan for the Guardian makes clear. Smaller countries like the UK are doing well too. That’s the way the whole world is moving. And therein lies our real problem with Mr Donald Trump. “Drill, baby drill!” is a policy based on the psychology of nostalgia, not science. One day it will have to be reversed. At what cost?

https://www.theguardian.com/environment/article/2024/jul/30/renewables-overtake-fossil-fuels-to-provide-30-of-eu-electricity

Life on Mars? Well David Bowie’s eponymous song was a long time ago. But not so long as these billions-of-year-old spots discovered by the Perseverance rover at Mars’ Neretva Vallis formation. Were they alive? Scientists are being very cautious, as Ian Sample explains for the Guardian. But when Bowie released his ditty back in 1971, it was almost heresy to suggest life anywhere in our star system. Now Mars, Europa, and Enceladus head a list of real hopefuls. Wahttps://www.theguardian.com/science/article/2024/jul/26/nasa-rover-discovery-hints-at-ancient-microbial-life-on-marstch this space, as they say.

Well, we won’t be rounding up every week. But every so often we hope to bring you these little clutches of news which show our side is still out there-and keeping busy.

#cancer #fusobacterium #sepsis #antibiotics #reneables #global warming #donald trump #mars #astrobiology #david bowie

Thanks for all the likes to that (slightly peevish) last post

Well…..we weren’t expecting that. After publishing out last little post Six Mysteries which could do us all in, or whatever, we had our doubts. Was the tone all a bit …..admonitory? A bit peevish, like someone who had risen too early and really wanted to go back to bed. Too late! And we set off on our little rounds, you know, shopping, a few scaffolders to chase up, that sort of thing.

Imagine thereby our surprise at the flood of warm and approving comments we got, not only from the usual sources, however welcome the latter are. Many of you who put out serious multimedia websites in far-away America, on any number of serious subjects, took time to notice this one.

We must have got something right. Maybe our species really does need to stop trying so hard, and to think a bit more.

Anyway, as the say in the readers letters columns in the Financial Times Saturday magazine : “Keep ’em coming” We were quite impressed by some of your sites and blogs. Keep them coming too. We few, we happy few, may yet make a difference

THE EDITORIAL BOARD

Six insoluble mysteries which may end us all

Occasionally we come across websites with lurid titles like “10 UNSOLVED MYSTERIES TO GIVE YOU THE HEEBIE JEEBIES!” And it’s all to do with odd bits of old stone or dodgy claims about flying crockery. Which made us think of a few everyday mysteries about Homo sapiens which are enough to give anyone the aforesaid Heebies, with a few jeebies thrown in for good measure. Because if we do not develop the cognitive capacity to solve them, we could well be heading for the biological equivalent of the junkyard,

(1) Where is the line between the individual and society? Countries that go too far towards prizing the State end up economically stagnant, as the society is captured by a small self-serving elite who grab all the resources. (Think USSR or Venezuela) On the other hand societies with no idea of the common good, where untaxed individuals run around doing what they like, not only end up without worthwhile armies or roads. They also get captured by an elite, this time billionaires, with almost identical outcome to the deluded Commies. No one has resolved this tension in any stable way.

(2) Emotion utterly dominates reason. All the technological and scientific advances that make life worth living (you really wanna give up soap, huh?) are formed in the reasoning part of the brain. Yet most people are driven by deep tides of emotion welling up from the subconscious. These rarely lead to anything profitable, and are the principal causes of most of the obsessions, addictions and generational hatreds which form such an immense drag on progress. Why is logic so weak and blind passion so strong?

(3) The drive to divide into hostile groups We often allude to this one; think football supporters and the Robbers Cave experiment. The American writer James Baldwin saw identity as a serious trap, denying us our own better nature. It may take all the AI in the world to solve this one

(4) The constant need for persecution of others, particularly the weak or disabled. Anyone still deluded about “the moral superiority of the oppressed” could learn from what happens to disabled neighbours in cheap housing estates, and how the noble proletarians make their lives utter hell. Why does everyone want justice, but only for themselves?

(5) The local and the trivial Why do so many people spend so much time learning about the lives of celebrities in tacky media outlets, when they would profit much more from reading magazines like The Economist or Science?

(6) An utter inability to change minds Most people are really rather deft and clever about what is around them; the hierarchies around their neighbours, families, jobs, and so on. But most of what they learned about bigger things like science or society was laid down decades ago. And the habits of mind formed in youth seem impossible to change, even when the survival need to do so becomes clear. This may ultimately be the most dangerous mystery of them all.

No species, however successful it seems at its peak, can long survive the competition from a better-adapted one. Our predecessor Homo erectus had evolved into top predator, and colonised three continents. Before it was utterly outclassed by the more intelligent Homo sapiens in its various subspecies. A newer, more intelligent form of human, perhaps incorporating elements from artificial intelligence and genetic engineering should be able to solve the above cognitive problems with ease. If that happens, there will be little enough space for the predecessor, and no motive to preserve us either.

#climate change #learning #cognition #human evolution #unsolved mysteries

Element 120? We stand in awe

One of the earliest memories of the school science lab was to see the Periodic Table for the first time. You know, that forbidding-looking chart of squares and funny, recondite little symbols like Mn and Cs, all arranged in a curious array of lines and columns. A long way from the everyday world of glam rock, flared trousers and playground rivalries about football teams and Ben Sherman shirts.

Those who looked slightly beyond the immediate would know that change was coming. NASA kept landing on the moon. And some very clever people were trying hard to push this same periodic table beyond its natural limit of 92 and make artificial elements with far more protons than could be found in nature. Fast forward fifty five years or so, and we suddenly realise how far they have got. Read this from Nature Briefings: Heaviest Element Yet within reach

Researchers have demonstrated a new way to make superheavy elements, opening the door to creating the heaviest element ever and adding another row to the periodic table. Scientists used a beam of titanium to make a known superheavy element, livermorium — element 116. If they’re able to make elements 119 and 120, as planned after an equipment upgrade, they will be the first documented from the eighth ‘period’. In this row, scientists expect to find atoms with so-far unseen electron configurations.Nature | 7 min read
Reference: arXiv preprint

It really is worth clicking on the link, gentle readers. If only to see a group of people performing at the best levels which our species can. Co-operating. Multinational. Thinking differently. Counter-intuitive-hell, what is a”titanium beam” anyway? That’s how progress comes. Just thinking again, in the old tired ways, the channels laid down as a child, will get us nowhere. Except, perhaps, backwards. The periodic table really can go beyond 92. Petrol really is bad for your health. Old allegiances will threaten your survival, if you’re not careful. Time to think as these scientists have done,

#nuclear physics #periodic table #research #chemistry

6 Problems which require global response,and only a global response

“You can’t stop me smoking! It’s an assault on my liberty!” It was a common cry in the early days of trying to save the world from tobacco pollution. Somehow the smokers never considered that that the toxic fumes they spread might inflict upon the liberties of others. Smoking is the world in miniature. For the same self-centred mindset may be found in those who cannot think beyond the boundaries of their own religious or ethnic group. So here are 6 problems which affect us all, and each of which will only be solved by deliberate acts of collective action, however cognitively difficult that may prove for some people.

1 Pollution As my country pumps out toxic metals, sh*t, plastics or whatever, it will get into the water, air and land of surrounding countries, poisoning their unfortunate inhabitants. If you don’t want to breathe someone else’s smoke, ways will be have to be found of asking people to stop. And to keep them stopped. Agreements, anyone?

2 Global Warming A subset of pollution really, except that we are only talking about carbon dioxide and methane. But as the water levels rise and the ocean currents collapse, you will have the comfort of blaming someone else. And they can blame you. Will you feel better?

3 Migration As we have said before, the real cause of this is imbalances in living standards between different parts of the planet. Successful transfers of wealth to the areas where migrants come from will slowly but surely eliminate the problem. How many Germans migrate to Iraq, for example?

4 Knowledge and fakery Since the invention of the Interweb and the subsidiary technologies that feast upon it, the world has been plagued by a deluge of fakes. Fake news stories, fake scientific papers, fake images and the utterly uninformed opinions thereby generated. Only a single world reference library with the veracity of its contents contents carefully agreed by all will allow a single reliable point of reference. This won’t be perfect, but will allow a fresh starting point, and mimics the way that single standards of things like currencies and weights and measures slowly ameliorated the human condition

5 The next pandemic Everyone agrees it’s coming, the question is where and when does it start. IT will probably be a virus. But could our hoary old favourite, an antibiotic-resistant superbug, be the killer?

6 Inequality As long as the super-rich can move their money and their yachts from jurisdiction to jurisdiction, the rest of us will never see a fair share of the wealth which we have created. Hence the shortages of things like hospital beds, school places, decent roads, etc.A single world taxation and financial authority would not only eliminate this problem, it would rapidly provide the resources to deal with those discussed above.

National sovereignty, tribal identity or whatever are extremely powerful forces in human affairs. And we ignore them at our peril, as we have oft-times warned on these pages. But they are also licences to pollute. Are we clever enough to reconcile the the conflict?

#pollution #global warming #climate change #antibiotics #pandemic #poverty