Once again we are indebted to that excellent organisation Nature Briefing for this opportunity to showcase another giant step forward for that old LSS favourite CAR-T therapy. [1]Well, three steps actually: as you will find out if you read this extract which they have titled One CAR-T to cure them all
| A woman with an ultra-rare combination of three autoimmune diseases has had no symptoms since receiving a single dose of engineered immune cells. Researchers used the woman’s own T cells to develop chimeric antigen receptor (CAR) T cells that targeted a protein on her B cells — the culprits behind her trifecta of autoimmune conditions. The woman experienced no side effects from the treatment, and fourteen months on she doesn’t take any medication for her conditions, says haematologist Fabian Müller, who helped to develop the treatment.Nature | 5 min read Reference: Med paper |
Breakthroughs like this don’t come from wishful thinking, magical explanations, or comforting stories about how the world ought to work. They come from the scientific method: from hypotheses that can be tested, data that can be challenged, and results that must survive scrutiny. When we follow that discipline, we get therapies that save lives. When we don’t, we get nothing but anecdotes and disappointment. The contrast speaks for itself We have other tasks for other publishers today, and must attend to them But we hope the foregoing leaves you with a tiny quantity of Hope
[1]CAR T-cell therapy | Cancer Research UK
#CAR-T #cancer #medicine #science #health #reason #auto immune disease
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